NOXXON Pharma is a biotechnology company whose core focus is on cancer treatment. NOXXON is using its proprietary class of drugs called Spiegelmers* to target the tumor microenvironment, a new frontier in cancer treatment. NOXXON's goal is to significantly enhance the effectiveness of cancer treatments including immuno-oncology approaches such as immune checkpoint inhibition and current standards of care such as chemotherapy and radiotherapy.
NOXXON's Spiegelmer platform has generated a broad proprietary pipeline of clinical-stage assets including its lead cancer candidate NOX-A12 and additional candidates outside oncology: Pipeline
2015, July 14
NOXXON appoints Aram Mangasarian as CEO
• Spiegelmer Inhibition of MCP-1/CCR2 - Potential as an Adjunct Immunosuppressive Therapy in Transplantation.
• Intravitreal inhibition of complement C5a reduces choroidal neovascularization in mice.
• Crystal structure of a mirror-image L-RNA aptamer (Spiegelmer) in complex with the natural L-protein target CCL2.